Hydroquinone bis2hydroxyethylether not listed as a carcinogen by acgih, iarc, ntp, or ca prop 65. If eye irritation persists get medical adviceattention store in a well ventilated place. These enzymes exhibit both a hydroquinone nadh oxidase activity and a protein disulfidethiol interchange activity in series, with each activity cycling every 22 to 26 minutes scarlett et al. P202 do not handle until all safety precautions have been read and understood. Pure hydroquinone does not readily form a vapor at room temperature.
Hydroquinone material safety data sheet cas no 123319. There is insufficient evidence for classifying hydroquinone as a. The dust my cause irritation of the nose, throat and upper respiratory tract. Section 14 transport information us dot shipping name. The occupational safety and health administrations osha hazard communication standard 29 cfr 1910. Clinical director, innovative skincare topical hydroquinone is used frequently throughout the world as a skin bleaching agent. Hydroquinone is a phenolic compound, which is naturally found in coffee, tea and wine.
Hydroquinone material safety data sheet cas no 123. It is formed in large quantities by chemical reduction of benzoquinone. May cause dizziness, nausea, sense of suffocation, increased. Hydroquinone safety data sheet according to federal register vol. Safety data sheets sdss environmental health and safety. Headaches, dizziness, nausea, and cyanosis may result from overexposure to vapor. No warranty, express or implied, is made and qorpak assumes no liability resulting from the use of this msds. Material safety data sheet hydroquinone msds finar limited. In humans, ingestion of 1 gram of hydroquinone has caused tinnitus, nausea, vomiting, shortness of breath, cyanosis, convulsions, delirium, and collapse. All chemicals may pose unknown hazards and should be used with caution.
Hydroquinone cas no, 123319 is defined as the aromatic organic compound that conforms to the formula in figure 1. S 26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Safety data sheet according to 19072006ec, article 31 trade name. Safety data sheet vos2 1 product and company identification alliance group, inc. There is insufficient evidence for classifying hydroquinone as a suspected carcinogenic or mutagenic substance in humans. Qualitative and quantitative estimation of hydroquinone in. Our msds database is an easy to use, do it yourself tool, and best of all.
Provide general dilution or local exhaust ventilation in. Volatilization of hydroquinone from water to the atmosphere will be too slow to be environmentally important. The international agency for research on cancer iarc has classified hydroquinone in. Methylhydroquinone 95716 msds report, methylhydroquinone msds safety technical specifications search, methylhydroquinone safety information specifications ect. Not classifiable as to its carcinogenicity to humans. Product and company identification product name perichem developer product. A schimadzu lc9 was used with uv detector set at 295 nm having ods column 25 cm. May cause severe irritation of the digestive tract. Occupational exposure to hydroquinone may occur by inhalation or dermal contact, especially in those who develop black and white film, since hydroquinone. Safety data sheet according to federal register vol. This compound is a generalpurpose inhibitor, stabilizer, antioxidant, and intermediate. Crystalbond 555 only available as paper copy, see binder in bard 316. All spectrum chemical usp grade products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities.
Occupational exposure to hydroquinone may occur by inhalation or dermal contact, especially in those who develop black and white film, since hydroquinone is a common component of developing solutions hsdb, 2005d. The mobile phase was a mixture of water and ethanol 45. Safety data sheet creation date 26sep2009 revision date 18jan2018 revision number 4 1. Material safety data sheet west liberty university. It is currently reported to function as an antioxidant, fragrance ingredient, hair colorant, reducing agent, and skin bleaching agent. If released to the atmosphere, hydroquinone will undergo direct photochemical degradation. Safety data sheet 2ethylhexyl acrylate date prepared. Hydroquinone was not safe for use in leaveon, nondrug cosmetic products. Our payment security system encrypts your information during transmission. It is topically applied to treat melisma, freckles and senile lentigines. The international agency for research on cancer iarc has classified hydroquinone.
No loss of hydroquinone was seen from filters spiked with 720 g hydroquinone, and then used to sample. No increases in cancer rates were observed in an epidemiology study which looked at mortality among more than 800 persons employed primarily in the manufacture of hydroquinone. Hydroquinone msds material safety data sheet or sds, coa and coq, dossiers, brochures. Hydroquinone will undergo direct photolysis in water, and it may be degraded in water by oxidative processes.
Rats and mice were given hydroquinone by stomach tube or at high concentrations in the diet. May cause dizziness, nausea, sense of suffocation, increased respiratory rate, vomiting, pallor, muscle twitching, cyanosis bluish discoloration of skin due to deficient oxygenation of the blood, delirium. Central drug house p ltd 728 vardaan house new delhi2 india. Hydroquinone is a skin, eye, mucous membrane, and gastrointestinal irritant. The information contained within this msds applies only to the bcc products product to which the sheet relates. Oh find msds or sds, a coa, data sheets and more information. Eastman hydroquinone, photographic grade, is a white crystalline solid.
Find msds or sds, a coa, data sheets and more information. Material safety data sheet hydroquinone 6 information in this msds is from available published sources and is believed to be accurate. The information contained in this material safety data sheet is based upon available data and believed to be correct. Get medical adviceattention p310 immediately call a poison centerdoctor p330 if swallowed, rinse mouth. Responses were not consistent across route of exposure, species or sex. Safety data sheet cytotoxic drugs have also been associated with negative health effects for developing fetuses, including higher incidences of spontaneous abortions, congenital. Hydroquinone is linked to exogenous ochronosis, dermatitis and skin. To adequately address safe handling, all information in this msds must be. Confirmed animal carcinogen with unknown relevance to humans.
Section 12 ecological information section disposal considerations dispose of in a manner consistent with federal, state, and local regulations. Identification of the substancemixture and of the companyundertaking 1. Page 5 of 7 genotoxicity in vivo mouse oral micronucleus test laboratory experiments have shown mutagenic effects. Hydroquinone, also known as benzene1, 4diol, is an aromatic organic compound which is a type of phenol, having the chemical formula c6h4oh2. Death has occurred in some individuals after ingestion of 5 grams of hydroquinone. Cornell ehs provides campus wide access to chemwatch, an online safety data sheet sds database consisting of over 250,000 chemwatch authored documents, and million vendor supplied documents. It may be found in concentrations up to 15% or more but a doctors prescription is required by the fda united states for. It can lighten everything from freckles and acne scars to postinflammatory marks caused by conditions like eczema.
Hydroquinone, usp is an effective topical medicine used to treat dark colored patches, freckles, and spots on the skin that appear due to sun exposure. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. This material safety data sheet msds applies only to the material as packaged. Material safety data sheet hydroquinone 2 ingestion. Chronic exposure to hydroquinone at higher levels has caused brownish discoloration of the cornea and conjunctiva and distortion of the cornea, in some cases leading to decreased visual acuity and blindness. Other companies are charging thousands of dollars to set up accounts and give you. Material safety data sheet mono tertiary butyl hydroquinone mtbhq section 1 chemical product and company identification. Hydroquinone for cosmetic use is chemically synthesized. Material safety data sheet eastman chemical company. May cause irritation of the nose and respiratory tract.
Hydroquinone is used as a developing agent in photography and as an antioxidant in rubber and food. It is used in photographic, chemical and cosmetic industries. Hydroquinone is commonly used as a biomarker for benzene exposure. Material safety data sheet tertiary butylhydroquinonetbhq. Sds of hydroquinone, safety data sheets, cas 123319. Perichem developer safety data sheet 27271a6 issuing date. We dont share your credit card details with thirdparty sellers, and we dont sell your information to others. Amended safety assessment of hydroquinone as used in cosmetics. The user must determine suitability of this information for his application. Safety data sheet eastmantm hydroquinone, photographic grade version 2.
Members of the ectonox family, such as cnox, or enox1, are involved in plasma membrane transport pathways. Hydroquinone may cause allergic skin reaction and is moderately toxic if ingested or inhaled. Hydroquinone, usp hydroquinone, usp sds preparation date 10172016. Hydroquinone, 123319, laboratory chemicals, c6h6o2 by loba chemie, india. Material safety data sheet tertiary butylhydroquinonetbhq msds 1. Hydroquinone is an active allergen so repeated and prolonged exposure may cause skin sensitization. Sampling and analytical methods hydroquinone partially. The information provided is based on our best knowledge at the time of.